According to a study published in the Annals of Internal Medicine 2014, older adults who have never been screened for Colon Cancer (23 percent of US elderly individuals), one-time screening appears to be cost-effective up to age 86 years.

This is based on a “modeling” simulation study that revealed that colonoscopy was cost-effective to age 83 years, sigmoidoscopy to 84 years, and fecal immunochemistry testing to 86 years for patients without comorbidity and at average risk for CRC. Colonoscopy was the most effective, and most expensive, strategy for one-time screening.